Diamet/Diamet SR Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Metformin HCl

Indications/Uses

NIDDM not responsive to diet control & w/ moderately elevated glycosylated Hb levels. Primary or secondary sulfonylurea failures as a single or in combination therapy w/ sulfonylureas. Very unstable juvenile or maturity onset diabetes in combination w/ insulin.

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Dosage/Direction for Use

Diamet 500 mg tds or 850 mg bd. Max: 2.5 g/day, may be increased gradually to 3 g/day. Diamet SR 1,000 mg once daily (evening). Should be increased by 500-mg increment wkly. Max: 2,500 mg once daily (evening).

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Overdosage

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Administration

Should be taken with food.

Contraindications

Hypersensitivity. CHF; acute or chronic metabolic acidosis including diabetic ketoacidosis w/ or w/o coma; dehydration, acute or chronic alcoholism. Renal & hepatic failure. Pregnancy & lactation.

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Special Precautions

Not to be used alone for IDDM. Not recommended in patients w/ severe thyroid function impairment. Concomitant use w/ cationic drugs. Promptly discontinue w/ CV collapse (shock), acute CHF, acute MI & other characterized by hypoxaemia. Suspend temporarily in any surgical procedure (except minor). Potentiated effects w/ alcohol. Avoid use in patients w/ evidence of hepatic disease. Pregnancy & lactation. Not recommended in childn <17 yr.

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Use In Pregnancy & Lactation

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Adverse Reactions

Anorexia, nausea & diarrhoea; impaired vit B12 absorption; metallic taste, wt loss; lactic acidosis.

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Drug Interactions

Concomitant use w/ cationic drugs eliminated by renal tubular secretion may affect renal function or result in significant haemodynamic change. Increased plasma conc w/ cimetidine, furosemide, nifedipine.

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Storage

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Description

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Action

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MIMS Class

Antidiabetic Agents

ATC Classification

A10BA02 - metformin ; Belongs to the class of biguanides. Used in the treatment of diabetes.

Regulatory Classification

POM

Presentation/Packing

Form

Diamet FC tab 500 mg

Packing/Price

10 × 10's

Form

Diamet SR FC tab 1 g

Packing/Price

10 × 10's

Form

Diamet SR FC tab 500 mg

Packing/Price

10 × 10's

Diamet/Diamet SR

metformin

Manufacturer:

BAL

Distributor:

Zizawa Healthcare